{"id":25617,"date":"2025-02-19T11:12:00","date_gmt":"2025-02-19T14:12:00","guid":{"rendered":"https:\/\/www.diariodepe.com.br\/xinhua\/?p=25617"},"modified":"2025-02-19T10:24:07","modified_gmt":"2025-02-19T13:24:07","slug":"cientistas-chineses-descobrem-esquema-complexo-do-cortex-cerebral-humano","status":"publish","type":"post","link":"https:\/\/diariodepe.com.br\/xinhua\/2025\/02\/19\/cientistas-chineses-descobrem-esquema-complexo-do-cortex-cerebral-humano\/","title":{"rendered":"Cientistas chineses descobrem esquema complexo do c\u00f3rtex cerebral humano"},"content":{"rendered":"\n<p>Beijing &#8211; Pesquisadores do Instituto de Automa\u00e7\u00e3o da Academia Chinesa de Ci\u00eancias revelaram a rela\u00e7\u00e3o intr\u00ednseca entre a estrutura topol\u00f3gica das conex\u00f5es do c\u00f3rtex cerebral humano e as caracter\u00edsticas gen\u00e9ticas, de acordo com um estudo publicado no Journal of Neuroscience.<\/p>\n\n\n\n<p>&nbsp; &nbsp;Fan Lingzhong, pesquisador do instituto, explicou que as redes neurais operam \u00e0 medida que os humanos pensam, aprendem ou percebem o mundo, com trilh\u00f5es de conex\u00f5es que permitem a r\u00e1pida transfer\u00eancia de informa\u00e7\u00f5es.<\/p>\n\n\n\n<p>&nbsp; &nbsp;O estudo aborda uma quest\u00e3o fundamental: como essas conex\u00f5es intrincadas se formam e por que regi\u00f5es cerebrais distintas exibem uma distribui\u00e7\u00e3o t\u00e3o ordenada atrav\u00e9s do c\u00f3rtex?<\/p>\n\n\n\n<p>&nbsp; &nbsp;&#8220;O c\u00e9rebro come\u00e7a a seguir um &#8216;projeto&#8217; gen\u00e9tico durante o desenvolvimento embrion\u00e1rio&#8221;, observou Fan.<\/p>\n\n\n\n<p>&nbsp; &nbsp;Os pesquisadores propuseram uma hip\u00f3tese: a codifica\u00e7\u00e3o gen\u00e9tica e a conectividade cortical n\u00e3o est\u00e3o diretamente correlacionadas devido \u00e0 vasta disparidade num\u00e9rica entre genes e conex\u00f5es neurais. Em vez disso, os genes provavelmente guiam a organiza\u00e7\u00e3o espacial dos tratos de fibras da subst\u00e2ncia branca por meio de princ\u00edpios organizacionais eficientes, formando padr\u00f5es espec\u00edficos embutidos no c\u00f3rtex, disse Li Deying, principal autor do artigo e estudante de doutorado no instituto.<\/p>\n\n\n\n<p>&nbsp; &nbsp;Ao analisar conjuntos de dados abrangentes, a equipe identificou tr\u00eas eixos topol\u00f3gicos dominantes que governam a conectividade cerebral: dorso-ventral, \u00e2ntero-posterior e medial-lateral.<\/p>\n\n\n\n<p>&nbsp; &nbsp;Esses eixos n\u00e3o apenas refletem padr\u00f5es de conex\u00f5es corticais, mas tamb\u00e9m se alinham estreitamente com gradientes morfogen\u00e9ticos e gen\u00e9ticos embrion\u00e1rios durante o desenvolvimento, disse Li.<\/p>\n\n\n\n<p>&nbsp; &nbsp;Uma descoberta importante do estudo, enfatizou Fan, \u00e9 a defini\u00e7\u00e3o de uma &#8220;topologia de conectividade global&#8221; em todo o c\u00e9rebro, que mostra correspond\u00eancia significativa com a express\u00e3o g\u00eanica.<\/p>\n\n\n\n<p>&nbsp; &nbsp;Isso sugere que os genes influenciam a conex\u00e3o neural complexa por meio de regras simplificadas, o que implica que a organiza\u00e7\u00e3o do c\u00e9rebro segue uma regra invis\u00edvel moldada pela gen\u00e9tica.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Beijing &#8211; Pesquisadores do Instituto de Automa\u00e7\u00e3o da Academia Chinesa de Ci\u00eancias revelaram a rela\u00e7\u00e3o intr\u00ednseca entre a estrutura topol\u00f3gica das conex\u00f5es do c\u00f3rtex cerebral humano e as caracter\u00edsticas gen\u00e9ticas, de acordo com um estudo publicado no Journal of Neuroscience&#8230;.<\/p>\n","protected":false},"author":3,"featured_media":25618,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-25617","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cultura-tecnologia"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cientistas chineses descobrem esquema complexo do c\u00f3rtex cerebral humano - Xinhua - Diario de Pernambuco<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/diariodepe.com.br\/xinhua\/2025\/02\/19\/cientistas-chineses-descobrem-esquema-complexo-do-cortex-cerebral-humano\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cientistas chineses descobrem esquema complexo do c\u00f3rtex cerebral humano - Xinhua - Diario de Pernambuco\" \/>\n<meta property=\"og:description\" content=\"Beijing &#8211; Pesquisadores do Instituto de Automa\u00e7\u00e3o da Academia Chinesa de Ci\u00eancias revelaram a rela\u00e7\u00e3o intr\u00ednseca entre a estrutura topol\u00f3gica das conex\u00f5es do c\u00f3rtex cerebral humano e as caracter\u00edsticas gen\u00e9ticas, de acordo com um estudo publicado no Journal of Neuroscience....\" \/>\n<meta property=\"og:url\" content=\"https:\/\/diariodepe.com.br\/xinhua\/2025\/02\/19\/cientistas-chineses-descobrem-esquema-complexo-do-cortex-cerebral-humano\/\" \/>\n<meta property=\"og:site_name\" content=\"Xinhua - Diario de Pernambuco\" \/>\n<meta property=\"article:published_time\" content=\"2025-02-19T14:12:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/diariodepe.com.br\/xinhua\/wp-content\/uploads\/sites\/3\/2025\/02\/202502193b91f7999a7748acae4b0e8065c54a5f_XxjwspP007016_20250219_CBMFN0A001.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"900\" \/>\n\t<meta property=\"og:image:height\" content=\"600\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Marcelo Oliveira de A. 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